Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

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Conclusion:
C5 plays an important role in glaucoma, with its deficiency lessening disease severity. These results highlight the importance of fully understanding the role of the complement cascade in neurodegenerative diseases. Inhibiting C5 may be beneficial as a therapy for human glaucoma. (Source: Journal of Neuroinflammation)