Large Clinical Trials Important But JAMA Article Recommendations Are Off-base

There was a time when drugs could be approved based on their ability to alter favorably biomarkers that are indicative of disease. For example, if a drug lowered bad cholesterol (LDL), it could be approved as it was assumed that by lowering LDL it would also be reducing cardiovascular risk. Similarly, a drug which lowered blood sugar levels would be thought to lower the risk of type 2 diabetes and prevent subsequent diabetic complications like blindness, kidney failure and heart disease. (Source: Forbes.com Healthcare News)MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.
Source: Blindness