Ivermectin‐induced blindness treated with intravenous lipid therapy in a dog

ObjectiveTo report a case of blindness due to the ingestion of ivermectin and subsequent successful treatment with intravenous lipid (IVL) therapy.
Case SummaryA female neutered Jack Russell Terrier was examined for acute onset of apparent blindness after being exposed to ivermectin the previous day. The dog appeared to be blind during initial examination. Pupillary light reflex, menace response, and dazzle reflex were not present in either eye. Fundic examination revealed small areas of linear retinal edema. Electroretinography (ERG) showed diminished activity in both eyes. Ivermectin was present in the serum on toxicological assay. Approximately 20 hours after exposure, IVL was infused. Within 30 minutes of initiating the infusion, the pupillary light reflexes returned in both e…
Source: Blindness